Rita Allen Foundation

NEWS

Mark Zylka and His Colleagues Make an Important Research Finding in the Pain Field

October 2008

Milton E. Cassel Scholar, Mark Zylka and his colleagues found that Prostatic Acid Phosphatase (PAP) is expressed in pain-sensing neurons and suppresses pain eight times more effectively than morphine. PAP was previously thought to function only in the prostate and was used as a diagnostic marker for prostate cancer. Their paper describing PAP in pain mechanisms was published as the cover article in the October 9, 2008 issue of Neuron.